cancer genes from stem cells
Researchers at the Whitehead Institute for Biomedical Research in Massachusetts successfully removed stumbling block in using pluripotent stem cells by taking out potentially cancer causing genes. The pluripotent stem cells could be made from a patient's own skin cells that reducing the chances of the body's immune system might reject the cells as it sometimes does with organ transplants. Scientists have learned that just a handful of genes can reprogram a cell back to a state in which, like an embryonic stem cell, it can generate any type of cell in the body. But the researchers said, these genes have the potential to cause cancer and also may interact with unpredictable results with thousands of other genes in the cell.
The Whitehead Institute team used viruses to transfer 3 genes into the skin cells of Parkinson's patients then removed them after they had done their job. The result was a batch of cells that looked like embryonic stem cells from Parkinson's patients, without the extra genes.
The Whitehead Institute team used viruses to transfer 3 genes into the skin cells of Parkinson's patients then removed them after they had done their job. The result was a batch of cells that looked like embryonic stem cells from Parkinson's patients, without the extra genes.
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