Long term study confirms Vioxx heart risks
- Form an analysis its found that, people who took the arthritis drug Vioxx having a chance of strokes or heart attacks. But there is a good news that The risk goes back toward normal after a year of follow up," said Dr. Robert Bresalier of the M.D. Anderson Cancer Center at the University of Texas, whose study appears in the journal Lancet.
A 2005 analysis by Bresalier and colleagues published in the New England Journal of Medicine suggested that it took 18 months for the drug to increase the risk of heart attacks and strokes, a time frame that played a prominent role in Merck's legal defense of Vioxx. - This data shows you can't precisely determine the timing of the risk. It does appear to start relatively early," he said in a telephone interview. The study, dubbed Approve, looked at the effects of three years of treatment with Vioxx, or rofecoxib, in 2,587 patients. Patients were checked for side effects while on the drug and two weeks after they stopped. It includes one-year follow-up data on patients who stopped taking the drug because of heart side effects.
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